The global preparative and process chromatography market is poised for substantial growth, with projections indicating an estimated market size of USD 14.53 billion by 2034, up from USD 9.93 billion in 2024. Despite a modest compound annual growth rate (CAGR) of 3.9% from 2024 to 2034, the market is expected to expand significantly due to increasing demand for monoclonal antibodies and their widespread acceptance in the pharmaceutical and biotechnology sectors.
Preparative and process chromatography plays a critical role in the efficient purification of biomolecules and pharmaceutical compounds across various industries, including biotechnology, pharmaceuticals, and food. The market’s growth is driven by technological advancements in chromatography methods, stringent regulatory standards, and the growing importance of high-quality products in chemistry, biology, forensics, and pharmaceutical sectors.
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Mechanistic modeling techniques have also been made easier by notable advancements in scientific knowledge, analytical skills, and computing power in the biotechnology field. End users have taken a remarkable interest in the new, industrially applicable monoclonal antibody-cation exchange (CEX) technology.
Surge in Production Demands Drives Innovation: The ever-growing production demands within these end-use industries are further stimulating innovation and adoption of preparative and process chromatography solutions.
Multiple Industries Fuel Demand for Efficient Purification
Beyond monoclonal antibodies, preparative and process chromatography is experiencing a broader surge in demand across various sectors. This is driven by several trends:
- Advancements in Chromatography Techniques: Technological innovations are constantly improving the efficiency and accuracy of chromatography methods.
- Stricter Regulatory Requirements: Regulatory bodies are enforcing stricter standards, necessitating high-precision purification techniques like preparative and process chromatography.
- Growing Focus on Quality: Across industries like biotechnology, pharmaceuticals, and food, the emphasis on superior product quality is intensifying. Preparative and process chromatography ensures this quality by delivering exceptional purification capabilities.
Innovation Fueled by Increasing Production Demands
The ever-growing production demands within these end-use industries are further accelerating the development and adoption of preparative and process chromatography solutions. As manufacturers strive to meet rising production targets, these advanced purification techniques become increasingly essential.
Key Takeaways from FMI’s Preparative and Process Chromatography Market Report
- Gas chromatography forecasted to remain the most sought-out technique among end-users.
- Centrifugal Partition Chromatography (CPC) is expected to metamorphose into a prominent alternative to purification processes owing to its high loading capacity and low solvent consumption.
- Increased preference for Simulated Moving Bed (SMB) chromatography to channel a significant portion of revenue.
- North America and Europe are expected to cumulatively account for over 60% of global market share
Preparative and Process Chromatography Market- Key Trends
- Penetration of 3D printing has empowered market players to develop automated analytical methods, and the development of membrane-based 3D printed separation devices and other latest systems are bestowing substantial revenue opportunities.
- Fast Protein Liquid Chromatography (FLPC) is gaining remarkable traction in the purification of biomolecules, thereby ensuring healthy overall growth.
- Sprouting investments in emerging economies, especially Asia Pacific, is boosting the market growth.
Preparative and Process Chromatography Market – Region-wise Outlook
- North America to prevail as the largest regional market through the forecast period, ascribed to high funding for research in life sciences.
- Europe is expected to remain the second most lucrative region owing to the strong presence of market players seeking collaborations and expansion.
- South Asia and East Asia are projected to exhibit tremendous growth potential during the forecast period, backed by increasing investments in biotechnology and pharmaceuticals in China and India.
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Preparative and Process Chromatography Market – Competitive Landscape
Key players operating in the preoperative and process chromatography market include Agilent Technologies, GE Healthcare, Pall Corporation, Merck KGaA, Thermo Fisher Scientific Inc., Shimadzu Corporation, Waters Corporation, Novasep Holding S.A.S, and Chiral Technologies, Inc. Market players are focusing on launching new products to strengthen their foothold, and are collaborating with other players to achieve the same.
On these lines, BIA Separations, in July 2020, signed agreements with IT Technologies Pte. Ltd., GeneX India Biosciences Pvt. Ltd. for the latter to distribute their products across Malaysia, Singapore, and India.
Preparative and Process Chromatography – Taxonomy
Type:
- Preparative chromatography(Consumables, columns, systems, services, resins)
- Process chromatography (consumables, columns, systems, services, resins)
End-use:
- Biotechnology & pharmaceutical industry
- Food & nutraceutical industry
- Academic research laboratories
Region:
North America
- U.S
- Canada
Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
Europe
- EU-5
- BENELUX
- Russia
- Poland
- Rest of Europe
South Asia
- India
- Pakistan
- Sri Lanka
East Asia
- China
- Japan
- South Korea
Oceania
- Australia
- New Zealand
Middle East & Africa
- GCC
- Turkey
- South Africa
- Rest of MEA
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