Global HER2 Positive Gastric Cancer Industry Poised to Hit US$ 1.78 Billion by 2033, Fueled by Alarming Upsurge in Gastric Cancer Cases | FMI Report

Global HER2 Positive Gastric Cancer Industry

The Global HER2 Positive Gastric Cancer Industry, valued at a significant US$ 1.26 Billion, is on track to experience remarkable growth, projected to reach US$ 1.78 Billion by the year 2033. This substantial expansion is anticipated at a Compound Annual Growth Rate (CAGR) of 3.5% between 2023 and 2033, according to recent market analysis.

Stomach cancer cells, particularly those classified as ‘HER2-positive,’ exhibit an excessive presence of the growth-promoting protein known as HER2 on their surface. Leveraging this understanding, treatments targeting the HER2 protein have emerged as a promising avenue in combating HER2-positive gastric cancers.

Regulatory authorities are actively contributing to this growth trajectory by approving innovative drugs designed to address HER2-positive gastric cancers. Notably, Enhertu, an antibody-drug conjugate product developed for the treatment of HER2-positive metastatic gastric cancers, received approval from the US Food and Drug Administration (FDA) in January 2021.

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The geriatric population is also contributing toward growth of HER2 positive gastric cancer market. There are vices like smoking and alcoholism to add (for all the age groups above teenage).

At the same time, the fact that there is still a lack of understanding regarding intratumoral heterogeneity and non-uniformity of regulations worldwide can’t be ignored. This factor may restrain the HER2 positive gastric cancer market going forward.

Future Market Insights has walked through these facts with future perspectives in its latest market study entitled ‘HER2 Positive Gastric Cancer Market’. It has its line of expertise in the form of analyst and consultants to look through the bottom-up approach in its primary, secondary, and tertiary modes of research.

“With a deeper focus on developing all the more effective treatment procedures along with advanced drugs, the global HER2 Positive Gastric Cancer Market is bound to grow on an irrevocable note in the forecast period”, says an analyst from Future Market Insights.

Key Takeaways from Global HER2 Positive Gastric Cancer Industry

  • North America holds the largest market share with the US housing a plethora of cancer-afflicted patients.
  • Europe and the Asia-Pacific stand second and third respectively on the similar grounds and the status quo is expected to remain unchanged even in the forecast period.

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Competitive Analysis

  • The US FDA, in May 2021, did access accelerated approval to pembrolizumab (Keytruda, Merck & Co.) in conjunction with fluoropyrimidine, trastuzumab, and platinum-containing chemotherapy for the very first line treatment of the patients with locally advanced metastatic or unresectable HER2 positive gastric/gastroesophageal junction (GEJ) adenocarcinoma.
  • CytoReason, in September 2022, did announce extending its multi-year partnership with Pfizer for using its AI technology for the latter’s drug development programs.
  • Shanghai Henlius Biotech, Inc., in December 2022, did announce about the first patient being dosed in phase 1 clinical trial (NCT053941168) of HLX53 (an anti-TIGIT Fc fusion protein) to treat metastatic solid tumors/lymphomas in China.
  • Novocodex Biopharmaceuticals is known for developing antibodies to treat cancer. The company is into designing biopharmaceutical anti-HER2 – a monoclonal antibody-conjugated drug via non-natural amino acid insertion technology to couple toxins on mAb. It could be used to treat HER2, gastric cancer, and positive recurrent breast cancer.
  • VCell makes provisions for biosimilar products to cure autoimmune diseases. Remsima is basically used for treating autoimmune diseases like ankylosing spondylitis and rheumatoid arthritis. Truxima anti-tumor biosimilar product is used for treating non-Hodgkin’s lymphoma and various other hematological tumors apart from rheumatoid arthritis. HER2 positive breast and gastric cancer could be treated through Herzuma.
  • Abscint does offer ABSCINT-HER2 to detect HER2 positive cells in brains. ABSCINT-206 is used to detect immune cells in granuloma CD-206 positive macrophages in heart.
  • ASLAN Pharmaceuticals is known for providing drugs to treat breast, bile duct, and gastric cancers. The most advanced compound is ASLAN001 that is pan-HER inhibitor with phase 2 data in gastric cancer. ASLAN002 does target RON (an immune checkpoint inhibitor) with cMET tyrosine kinases pertaining to breast and gastric cancer.

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What does the Report Cover?

  • The research study is based on therapy (chemotherapy, immunotherapy, radiation therapy, and targeted therapy), stage (Stage I, Stage II, Stage III, and Stage IV), and end-user (ambulatory surgery centers, hospitals and specialty clinics, and likewise).
  • With increasing approval of the pipeline candidates, the global HER2 positive gastric cancer market is expected to grow inadvertently in the forecast period.

Key Companies Profiled:

  • AstraZeneca
  • Bayer
  • Bristol-Myers Squibb
  • Ono Pharmaceutical Co. Ltd
  • Hutchison Medipharma
  • LintonPharm
  • Shanghai Henlius Biotech
  • Sanofi
  • Pfizer
  • Novartis AG

Key Segments Covered in Global HER2 Positive Gastric Cancer Industry Survey

Global HER2 Positive Gastric Cancer Industry by Therapy:

  • Chemotherapy
  • Immunotherapy
  • Radiation Therapy
  • Targeted Therapy

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Global HER2 Positive Gastric Cancer Industry by Stage:

  • Stage I
  • Stage II
  • Stage III
  • Stage IV

Global HER2 Positive Gastric Cancer Industry by End-User:

  • Ambulatory surgery centers,
  • Hospitals and Specialty clinics
  • Others

Global HER2 Positive Gastric Cancer Industry by Region:

  • North America
  • Latin America
  • Western Europe
  • Eastern Europe
  • Asia-Pacific
  • Middle East & Africa (MEA)

About Future Market Insights (FMI)

Future Market Insights, Inc. (ESOMAR certified, Stevie Award – recipient market research organization and a member of Greater New York Chamber of Commerce) provides in-depth insights into governing factors elevating the demand in the market. It discloses opportunities that will favor the market growth in various segments based on Source, Application, Sales Channel and End Use over the next 10-years.

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About the Author

Nikhil Kaitwade

Associate Vice President at Future Market Insights, Inc. has over a decade of experience in market research and business consulting. He has successfully delivered 1500+ client assignments, predominantly in Automotive, Chemicals, Industrial Equipment, Oil & Gas, and Service industries.
His core competency circles around developing research methodology, creating a unique analysis framework, statistical data models for pricing analysis, competition mapping, and market feasibility analysis. His expertise also extends wide and beyond analysis, advising clients on identifying growth potential in established and niche market segments, investment/divestment decisions, and market entry decision-making.
Nikhil holds an MBA degree in Marketing and IT and a Graduate in Mechanical Engineering. Nikhil has authored several publications and quoted in journals like EMS Now, EPR Magazine, and EE Times.

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