The Global PD-1/PD-L1 inhibitors Industry is poised for unprecedented growth, with a remarkable trajectory that is expected to propel it to a valuation of $123.3 billion by the year 2033. This substantial expansion is underpinned by a notable Compound Annual Growth Rate (CAGR) of 9.6% throughout the projected period, with a valuation of $49.5 billion anticipated for 2023.
The exponential rise in demand for PD-1 and PD-L1 inhibitors is primarily driven by the growing global burden of cancer. These essential immune checkpoint inhibitors are used as front-line treatments for a wide array of cancers, making them indispensable in the fight against this devastating disease.
One of the standout players in this market is Pembrolizumab, marketed as KEYTRUDA. This immunotherapy drug is in high demand worldwide, thanks to its proven efficacy in treating a wide range of FDA-approved disorders. It has become a beacon of hope for patients and healthcare professionals alike.
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The increased R&D activities are projected to generate considerable growth potential for key competitors in the Global PD-1/PD-L1 Inhibitors Industry.
Market participants, for example, are expanding their spending in research and development to fulfil increased demand.
- Anti-PD-1 and anti-PD-L1 immunotherapies for patients with metastatic melanomas are being developed by researchers at Johns Hopkins Kimmel Cancer Centre. The therapy’s purpose is not to directly destroy cancer cells, but to disrupt a route that protects tumour cells from immune system components capable of fighting cancer.
Key Takeaways
- The hospital pharmacies category is predicted to have a considerable market share of 48.3% over the projection period because to its vast client base, rising healthcare expenses, and rising cases of diseases such as lung and bladder cancer, melanoma, Hodgkin lymphoma, and others.
- By 2033, the United States is expected to generate US$ 23.4 billion in revenue. The government is increasing funding and support for cancer drug development. A boom in market research and development for new and innovative pharmaceuticals is also supporting regional growth.
- China is expected to be a lucrative market, with a 14.0% annual growth rate. The sale of approved therapies and the increasing occurrence of blood-related tumours are two of the key causes for the significant rise of the PD-1 and PD-L1 inhibitors market. Vendors’ rising patient support programmes are moving the market in this region ahead.
- Pembrolizumab is expected to grow at an 8.7% annual pace throughout the forecast period, reaching a significant market share of 49.5% in 2022. Pembrolizumab’s use has expanded due to its established efficacy in treating FDA-approved indications such as head and neck squamous cell cancer (HNSCC), non-small cell lung cancer (NSCLC), melanoma, and others.
- Tamil Nadu in India is developing a treatment policy to identify 66.0% of cancer patients in the first and second stages by 2030, allowing for proper treatment. As a result, such a policy is expected to fuel demand for PD-1 inhibitor drugs, propelling the growth of the segment over the forecast period.
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Manufacturers are Constantly Evolving Business Models
Companies in the Global PD-1/PD-L1 Inhibitors Industry are moderately competitive by nature, with several key players present. These players are part of several strategic alliances. The agreement and system automation speed up the manufacturer’s strategy to capitalize on market share and capture a sizable market share.
Key Players:
- Akeso Inc.
- Alphamab Oncology
- Amgen Inc.
- AstraZeneca Plc
- BeiGene Ltd.
- Bristol Myers Squibb Co.
- Chia Tai Tianqing Pharmaceutical Group Co. Ltd.
- Eli Lilly and Co.
- Others
Latest Developments
- Novartis International AG acquired The Medicines Company in January 2020. This acquisition aided Novartis in using a vaccine-like approach to treat the world’s leading cause of mortality and disability.
- Merck announced the FDA approval of KEYTRUDA, Merck’s anti-PD-1 therapy, in combination with chemotherapy, with or without bevacizumab, in October 2021. Patients with persistent, recurrent, or metastatic cervical cancer whose tumors express PD-L1 (Combined Positive Score [CPS] 1) as determined by an FDA-approved test are given the therapy.
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Global PD-1/PD-L1 Inhibitors Industry Segment by Category
By Product:
- Nivolumab
- Pembrolizumab
- Atezolizumab
- Avelumab
- Durvalumab
By Indication:
- Melanoma
- Non-Small Cell Lung Cancer (NSCLC)
- Renal Cell Carcinoma (RCC)
- Head and Neck Squamous Cell Cancer (HNSCC)
- Bladder Cancer
- Merkel Cell Carcinoma (MCC)
- Others
By Distribution Channel:
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
Author
Sabyasachi Ghosh (Associate Vice President at Future Market Insights, Inc.) holds over 12 years of experience in the Healthcare, Medical Devices, and Pharmaceutical industries. His curious and analytical nature helped him shape his career as a researcher.
Identifying key challenges faced by clients and devising robust, hypothesis-based solutions to empower them with strategic decision-making capabilities come naturally to him. His primary expertise lies in areas such as Market Entry and Expansion Strategy, Feasibility Studies, Competitive Intelligence, and Strategic Transformation.
Holding a degree in Microbiology, Sabyasachi has authored numerous publications and has been cited in journals, including The Journal of mHealth, ITN Online, and Spinal Surgery News.
About Future Market Insights (FMI)
Future Market Insights, Inc. (ESOMAR certified, recipient of the Stevie Award, and a member of the Greater New York Chamber of Commerce) offers profound insights into the driving factors that are boosting demand in the market. FMI stands as the leading global provider of market intelligence, advisory services, consulting, and events for the Packaging, Food and Beverage, Consumer Technology, Healthcare, Industrial, and Chemicals markets. With a vast team of over 5,000 analysts worldwide, FMI provides global, regional, and local expertise on diverse domains and industry trends across more than 110 countries.
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