The Global Cholesterol API Market is expected to be worth US$ 269.0 million by the end of 2022, with a 4.7% CAGR between 2022 and 2032. The global cholesterol API market is anticipated to be valued US$ 426.9 million by 2032. The market leaders are animal-derived sources, which will account for around 52.7% of the market in 2021.
Liposomes are an essential component of any drug delivery system due to their many advantageous qualities such as ease of manufacture, bilayer structure that assembles the cellular membrane, and excellent biocompatibility. Extensive efforts have been made to include cholesterol into liposome-based compositions.
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Cholesterol, as an essential component of any biological membrane, plays an important function in liposomal formulations. Liposomes containing more cholesterol are extremely stable.
During liposome formulation, criteria such as stability, size, and encapsulation efficiency are considered, according to a report published in December 2020 by Ascension Sciences. The amount of cholesterol in a liposome formulation considerably influences its stability. A higher cholesterol percentage promotes the production of bigger liposomes with lower encapsulation efficiency and higher drug retention.
Despite the fact that liposomes have a wide range of uses, including diagnosis, food items, gene transport, medication and vaccine delivery, and biosensor production, their use is severely limited due to their physicochemical instability. Cholesterol is essential for the integrity of a liposomal membrane.
Cholesterol also has an impact on fluidity, drug retention, phospholipid packing, transition temperature (Tm), permeability, elasticity, membrane strength, and plasma stability. Researchers plan to use cholesterol as a potential ingredient for liposome stability.
Because of the aforementioned factors, the worldwide cholesterol API market is expected to grow over the forecast period.
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Key Takeaways: Cholesterol API Market
- Because of their simple availability and low cost, the animal-derived sector had around 7% of the cholesterol API market share in 2021.
- By manufacturing process, the GMP segment is expected to account for around 9% of the market by 2032.
- The monoclonal antibodies segment by end user is expected to increase at a CAGR of 0% during the forecast period.
- From 2022 to 2032, the East Asian cholesterol API market is predicted to exhibit the highest CAGR of 6% among all other regions.
- During the forecast period, the US cholesterol API market is expected to rise at a lucrative CAGR of 6%.
“Rising demand for RNA vaccines and monoclonal antibodies is projected to drive growth in the next decade. Besides, increasing use of liposomal formulations in drug delivery systems is set to propel sales of cholesterol APIs across the globe,” says an analyst of Future Market Insights.
Competitive Landscape: Cholesterol API Market
The cholesterol API market is extremely fragmented, with a mix of regional, start-up, and established players. Key businesses are negotiating a huge number of agreements and engaging in mergers and acquisitions, as well as collaborations, to enhance their market share.
For instance,
- CordenPharma and Germany’s Otto-von-Guericke-Universität Magdeburg achieved a scalable synthesis of pharma-grade cholesterol in May 2021, which is utilised as part of the lipid cocktail for the assembly of successful mRNA-based vaccines.
- Evonik announced the €25 million first stage of a new long-term programme in May 2020 to satisfy Europe’s growing demand for contract manufacture of APIs and advanced intermediates.
Get More Insights on Cholesterol API Market
Future Market Insights offers a unique perspective and actionable insights on the cholesterol active pharmaceutical ingredient market in its latest study, presenting a historical demand assessment of 2017 to 2021 and projections for 2022 to 2032.
The research study is based on the source (animal-derived, plant-derived, and synthetic), manufacturing process (GMP and non-GMP), and end user (RNA vaccines, monoclonal antibodies, and others) across seven key regions of the world.
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Cholesterol API Market Outlook by Category
By Source:
- Animal Derived
- Plant Derived
- Synthetic
By Manufacturing Process:
- GMP
- Non – GMP
By End User:
- RNA Vaccines
- Monoclonal Antibodies
- Others
About Future Market Insights, Inc.
Future Market Insights, Inc. (ESOMAR certified, Stevie Award – recipient market research organization and a member of Greater New York Chamber of Commerce) provides in-depth insights into governing factors elevating the demand in the market. It discloses opportunities that will favor the market growth in various segments on the basis of Source, Application, Sales Channel and End Use over the next 10-years.
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