The global Graft Versus Host Disease (GvHD) Treatments market is poised for substantial growth, with an estimated valuation of USD 2,713.6 million in 2023. According to market forecasts, the market is expected to expand at a robust Compound Annual Growth Rate (CAGR) of 8.2% over the forecast period from 2023 to 2033, reaching approximately USD 5,960.7 million by 2033.
Graft versus host disease (GvHD) is a common complication following hematopoietic cell transplantation (HCT) where the donor’s immune cells attack the recipient’s tissues. The market’s growth is driven by increasing adoption of corticosteroids and combination therapies, advancements in medical treatments, and rising awareness about GvHD management.
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In December 2021, the US Food and Drug Administration approved Orencia (abatacept) for the management of GVHD in both adult and pediatric patients. Orencia is used to avoid autoimmune diseases as well as treat them. Through specific attachment to and modification of one of the key costimulation signals sent by these cells, this medicine circumvents the attack of T-cells, which are essential in acute GVHD.
As a result, T-cells are prevented from fully activating, hence preventing acute (GVHD). Surgeons are evaluating several new approaches to prevent (GVHD) in the future.
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Key Takeaways:
- The global graft versus host disease (GvHD) treatment market is expected to reach US$5.96 billion by 2033, growing at a CAGR of 8.2%.
- Rising adoption of combination therapies and advancements in allogeneic hematopoietic cell transplant (HCT) are key growth drivers.
- Newer medications like Jakafi and Rezurock offer improved efficacy for chronic GvHD compared to traditional treatments.
Recent improvements in acute graft-versus-host disease (GVHD) severity levels and overall survival rates may be advantageous for allogeneic hematopoietic cell transplant patients; nevertheless, a number of issues still need to be resolved. Furthermore, more recent drug approvals for the prevention and treatment of chronic (GVHD) include Jakafi and Rezurock, which may be more beneficial than earlier ones.
Key Segments Profiled in Market:
By Product:
- Monoclonal antibodies
- mTOR inhibitors
- Tyrosine kinase inhibitors
- Thalidomide
- Etanercept
By Disease:
- Acute Graft Versus Host Disease (aGvHD)
- Chronic Graft Versus Host Disease (cGvHD)
By Region:
- North America
- Latin America
- Europe
- Asia Pacific
- Middle East & Africa
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