The APOL1-mediated kidney disease market is poised for substantial growth, projected to escalate from USD 3779.9 million in 2023 to a remarkable USD 5753.9 million by 2033, boasting a forecasted Compound Annual Growth Rate (CAGR) of 4.3%. This surge underscores the urgent need for innovative therapies tailored to address the root cause of this debilitating condition.
APOL1-mediated kidney disease presents a critical healthcare challenge, characterized by limited treatment options that merely alleviate symptoms such as swelling, fluid retention, and hypertension. The primary culprit, excessive levels of the APOL1 protein, precipitates nephropathic symptoms and, inevitably, kidney failure. Addressing this underlying cause is imperative for transforming patient outcomes.
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In response to this pressing need, pioneering efforts are underway to develop targeted therapies aimed at reducing APOL1 protein levels in affected individuals. By addressing the fundamental molecular mechanism driving the disease, these novel treatments hold the potential to revolutionize the landscape of APOL1-mediated kidney disease management.
The market trajectory for APOL1-mediated kidney illness has been steadily ascending, with a valuation of US$ 3.0 billion in 2020. According to Future Market Insights (FMI), this upward trend is expected to persist, with a stable CAGR exceeding 4% projected over the forecast period (2020-2030). This sustained growth underscores the growing recognition of APOL1-mediated kidney disease as a significant healthcare concern demanding innovative solutions.
As stakeholders across the healthcare continuum unite in their commitment to combat APOL1-mediated kidney disease, the stage is set for transformative advancements that promise to enhance patient well-being and reshape the treatment landscape.
Key Takeaways from APOL1 Mediated kidney Diseases Market Study
- Chronic kidney diseases account for more than 95% of all the APOL1 mediated diseases. Increasing prevalence of hypertension associated kidney diseases will increase treatment needs over the forecast period
- North America accounts for over 3/4th of the global market. High prevalence of the disease among people with African American ancestry makes North America the leader in this market
- Pipeline drugs under development are targeted to be launched in the U.S., catapulting it as a highly lucrative pocket
- Key players are focusing on extensive research and development for targeted therapy towards APOL1
- The COVID-19 outbreak did not have any impact on the APOl1 mediated treatment market. All patients with indications like end stage kidney disorders were attended amidst COVID-19 due to the severity of kidney disease
“Increasing research and development for discovery of underlying cause of APOL1 mediated kidney disease and its targeted therapy will propel the market growth in the future,” says FMI analyst
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Who is winning? Collaboration is the key strategy amongst market players. Companies research on APOL1 therapies are strengthening their chances of successful clinical trials by collaborating with prominent pharma players. Increasing investments in drug discovery is expected to favor the growth the global market over the forecast period
- For instance, Ionis Pharma has collaborated with AstraZeneca for developing its molecule which is currently under clinical trial phase 1.
APOL1 mediated kidney diseases (Symptomatic Treatment) Market
By Indication:
- Chronic Kidney Disease
- Focal segmental glomerulosclerosis (FSGS)
- Human immunodeficiency virus (HIV)-associated Nephropathy
- Hypertension-associated Kidney Disease
- End-Stage Kidney Disease
Region
- North America (U.S.)
- Europe
- MEA
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About Future Market Insights (FMI)
Future Market Insights, Inc. (ESOMAR certified, recipient of the Stevie Award, and a member of the Greater New York Chamber of Commerce) offers profound insights into the driving factors that are boosting demand in the market. FMI stands as the leading global provider of market intelligence, advisory services, consulting, and events for the Packaging, Food and Beverage, Consumer Technology, Healthcare, Industrial, and Chemicals markets. With a vast team of over 400 analysts worldwide, FMI provides global, regional, and local expertise on diverse domains and industry trends across more than 110 countries.
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