The global cholesterol active pharmaceutical ingredient market is expected to grow steadily, reaching a projected value of US$445.3 million by 2033. Its significant increase from the estimated value of US$280.6 million in 2023 is the result of a 4.7% compound annual growth rate (CAGR).
When creating drugs to control cholesterol levels in patients with hyperlipidemia and cardiovascular disorders, cholesterol APIs are essential. The manufacturing of statins, fibrates, bile acid sequestrants, and other lipid-lowering medications used in the diagnosis, prevention, and treatment of atherosclerotic cardiovascular disease depends on these pharmaceutical chemicals.
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The anticipated growth in the global cholesterol API market can be attributed to several factors. The increasing prevalence of cardiovascular diseases, fueled by factors such as sedentary lifestyles, unhealthy dietary habits, and aging populations, is driving the demand for cholesterol-lowering medications. Additionally, advancements in pharmaceutical research and development, including the introduction of novel drug formulations and combination therapies, are expanding the market for cholesterol APIs
Government Programs Encourage Control of Cholesterol:
The increasing prevalence of CVDs is being actively addressed by governments and healthcare institutions around the world. Programs for screening for cholesterol, public awareness campaigns, and attempts to increase accessibility for cholesterol-lowering drugs are among the initiatives. The demand for cholesterol APIs has surged as a direct result of these initiatives.
Competitive Landscape:
There are many different firms in the highly fragmented worldwide cholesterol API market. In order to address the increasing demand from consumers and broaden their clientele, these businesses are employing several tactics such mergers and acquisitions, joint ventures, cooperative efforts, and the introduction of new products.
The following are a few recent changes in the worldwide cholesterol API market:
Sanofi Consumer Healthcare Korea and AB-BIOTICS collaborated in June 2023 to launch probiotics in South Korea that have benefits beyond enhancing intestinal health. Assisting people in controlling their cholesterol levels is its main goal. The Ministry of Food and Drug Safety has approved it as the first probiotic product. The South Korean market is renowned for being more open to using probiotics for a range of medical applications.
ProBiotix Health introduced a dual-action cholesterol pill in May 2023. This novel tablet lowers the absorption of dietary cholesterol while simultaneously assisting the liver in removing cholesterol from the bloodstream.
- In May 2022, Sun Pharma revealed that its fully-owned subsidiary is going to soon introduce a new oral medication called Bempedoic Acid in India. This drug is specifically designed to lower low-density lipoprotein (LDL) cholesterol levels. The subsidiary plans to market the drug in India using the brand name Brillo.
- The US Food and Drug Administration approved Regeneron Pharmaceuticals, Inc.’s Evkeeza in February 2021 to be used in conjunction with other treatments aimed at lowering low-density lipoprotein cholesterol (LDL-C) levels. Notably, Evkeeza is the first FDA-approved medication that binds to and inhibits the function of angiopoietin-like 3 (ANGPTL3), an essential protein involved in the metabolism of lipids.
- The signing of an R&D collaboration agreement to strengthen their position in the field of lipid nanoparticles (LNP) formulations was announced by CordenPharma and Wacker in December 2021.
- Centrient Pharmaceuticals, a top supplier of sustainable antibiotics and next-generation statins, began producing its innovative statins manufacturing facility in June 2021. To help satisfy the increasing demand for Rosuvastatin and Atorvastatin APIs, the business plans to quadruple its statin production capacity.
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Key Market Players
- Merck KGaA
- Cayman Chemical Company (Matreya)
- CordenPharma
- Croda International Plc (Avanti)
- NOF (Nippon Oil & Fats) Corporation
- Nippon Fine Chemical Co. Ltd.
- Akums Drugs & Pharmaceuticals Ltd
- Tokyo Chemical Industry Co., Ltd.
- Evonik Industries AG
- Dishman Group
- Hänseler AG
- Caesar & Loretz GmbH
- Fisher Scientific Co, LLC (Thermo Fisher)
Cholesterol API Market Outlook by Category:
By Source:
- Animal Derived
- Plant Derived
- Synthetic
By Manufacturing Process:
- GMP
- Non – GMP
By End User:
- RNA Vaccines
- Monoclonal Antibodies
- Others
By Region:
- North America
- Latin America
- Europe
- South Asia
- East Asia
- Oceania
- The Middle East and Africa (MEA)
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