The ESR1 mutated metastatic breast cancer diagnostics market size was estimated to be worth US$ 58.70 million in 2022 and is expected to increase to US$ 185 million between 2023 and 2033, growing at a CAGR of 11%. Due to the rising incidence of breast cancer and the increasing need for individualised treatment choices for patients with specific genetic mutations, the market for ESR1 mutant metastatic breast cancer diagnostics is growing. From 2018 to 2022, the market for diagnostics for metastatic breast cancer resulting from mutations in the ESR1 gene grew at a compound annual growth rate (CAGR) of 6.9%.
One of the key drivers of growth in the ESR1 mutated metastatic breast cancer diagnostics market is the increasing prevalence of breast cancer. Breast cancer is one of the most common types of cancer, affecting millions of people worldwide. According to the World Health Organization (WHO), breast cancer is the most common cancer among women globally, with an estimated 2.3 million new cases diagnosed in 2020 alone. As breast cancer continues to be a major public health concern, the demand for advanced diagnostic tools like ESR1 mutated metastatic breast cancer diagnostics is expected to rise.
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Advancements in diagnostic technology have also contributed to the growth of the ESR1 mutated metastatic breast cancer diagnostics market. In recent years, there have been significant advances in the field of cancer diagnostics, including the development of advanced imaging techniques and molecular diagnostic tests. These advancements have made it possible for medical professionals to identify ESR1 mutations more accurately and efficiently, allowing for earlier diagnosis and more personalized treatment options.
Another factor driving growth in the ESR1 mutated metastatic breast cancer diagnostics market is the increasing awareness of ESR1 mutations among medical professionals and patients. As medical research continues to uncover new information about breast cancer mutations, more healthcare providers are becoming aware of the importance of ESR1 testing. This increased awareness has led to greater demand for ESR1 mutated metastatic breast cancer diagnostics, as well as increased funding for research and development in this area.
Key Takeaways:
- The global ESR1 mutated metastatic breast cancer diagnostics market is expected to grow with an 11% CAGR from 2023 to 2033.
- By end user, diagnostic centres are expected to hold 47% of the market share in 2023 for ESR1 mutated metastatic breast cancer diagnostics market.
- North America is expected to possess a 45% market share for ESR1 mutated metastatic breast cancer diagnostics market in 2023.
- Europe ESR1 mutated metastatic breast cancer diagnostics market size is expected to possess a 40% market share in 2023.
Competitive Landscape:
Key players in the ESR1 mutated metastatic breast cancer diagnostics are Berlin-Chemie, Pfizer, Sanofi, G1 Therapeutics, Inc., Sun Pharma Advanced Research Company, Zenopharm, Arvinas, Sermonix Pharmaceuticals, Roche, AstraZeneca, Novartis, Zentalis Pharmaceuticals, Olema Pharmaceuticals
- Sanofi has developed a targeted therapy called SAR439859, which is currently being evaluated in clinical trials for the treatment of advanced breast cancer, including ESR1 mutated metastatic breast cancer. SAR439859 is an oral selective estrogen receptor degrader (SERD) that works by blocking the activity of the estrogen receptor (ER) protein, which is often overexpressed in breast cancer cells. The drug has shown promising results in preclinical studies, and it is currently being evaluated in several clinical trials to assess its safety and efficacy in breast cancer patients.
- G1 Therapeutics has been involved in the development of diagnostic tools to identify ESR1 mutations in breast cancer patients. In 2021, the company announced that it had entered into a collaboration with Guardant Health, a leading precision oncology company, to develop a liquid biopsy test for the detection of ESR1 mutations in circulating tumor DNA (ctDNA) from breast cancer patients.
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Key Segments :
By Hormonal Therapy:
- Tamoxifen
- Aromatase inhibitors
- Ovarian suppression
- Fulvestrant
- Elacestrant
By Chemotherapy:
- Capecitabine
- Carboplatin
- Cisplatin
- Cyclophosphamide
- Docetaxel
- Others
By Targeted Therapy:
- Monoclonal antibodies
- Small molecule inhibitors
- Tumor-agnostic treatments
- Immunotherapy
- Pembrolizumab
- Dostarlimab
By End User:
- Hospitals
- Clinics
- Research and Academic Institutes
- Diagnostic Centres
By Region:
- North America
- Latin America
- Europe
- South Asia
- East Asia
- Oceania
- Middle East & Africa
Author By:
Sabyasachi Ghosh (Associate Vice President at Future Market Insights, Inc.) holds over 12 years of experience in the Healthcare, Medical Devices, and Pharmaceutical industries. His curious and analytical nature helped him shape his career as a researcher.
Identifying key challenges faced by clients and devising robust, hypothesis-based solutions to empower them with strategic decision-making capabilities come naturally to him. His primary expertise lies in areas such as Market Entry and Expansion Strategy, Feasibility Studies, Competitive Intelligence, and Strategic Transformation.
Holding a degree in Microbiology, Sabyasachi has authored numerous publications and has been cited in journals, including The Journal of mHealth, ITN Online, and Spinal Surgery News.
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