Global Enzyme Replacement Therapy Industry Set to Eclipse US$ 13.8 Billion by 2028, Propelled by a Resilient 6.7% CAGR | Revealed by FMI

Global Enzyme Replacement Therapy Industry

The Global Enzyme Replacement Therapy Industry is anticipated to reach a value of US$ 9.3 billion in 2022 and, with a CAGR of 6.7%, US$ 13.8 billion by the end of 2028. Revenue from enzyme replacement therapy (ERT) represents over 63% of the market for hormone replacement globally. The usage of enzyme replacement therapy has been significantly influenced by the rise in the prevalence of uncommon disorders, and it is anticipated that medical research will further speed up this development.

Increasing per capita healthcare expenditure in North America is expected to push market revenue growth. The rapidly developing healthcare infrastructure and increasing awareness programmes in the highly populous regions of Asia Pacific and China are expected to play an important role in driving revenue growth of the Global Enzyme Replacement Therapy Industry.

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Global Enzyme Replacement Therapy Industry: Regional Insights

With nearly 25%-30% market share, North America dominated the Global Enzyme Replacement Therapy Industry in 2017, partly due to the presence of leading market players in the region. In developing regions such as Latin America, advancements in medical facilities are helping the region cope with the healthcare crisis. Medical facilities in Brazil are equivalent to hospitals in the United States, with some even exceeding American standards. Brazil offers everything from large, full-service hospitals to smaller, intimate private clinics.

Brazil has developed into a centre of excellence for healthcare in Latin America, with major universities that support research, teaching and training of medical professionals. Western Europe is the second largest market globally and is expected to be valued at US$ 2,893.2 Mn by 2028, with France, Italy and Spain projected to witness significant growth rates. Japan is expected to be the third largest market for enzyme replacement therapy.

Global Enzyme Replacement Therapy Industry: Segmentation & Forecast

The Global Enzyme Replacement Therapy Industry has been segmented based on therapeutic condition, route of administration, distribution channel and region. Therapeutic conditions in the enzyme replacement therapy markets include Fabry disease, Gaucher disease, mucopolysaccharidosis, Pompe disease, lysosomal acid lipase deficiency and others.

Globally, the mucopolysaccharidosis therapeutic condition is the most attractive segment. The injectable segment remains the most lucrative route of administration in the Global Enzyme Replacement Therapy Industry. Among all distribution channels for enzyme replacement therapy, speciality treatment pharmacies are expected to be the most lucrative, followed by hospital pharmacies.

Key Research Findings

Enzyme replacement therapy is used in the treatment of rare diseases and the global market is projected to create incremental opportunity of US$ 6,448.3 Mn between 2022 and 2028

When compared to other established markets such as North America, the enzyme replacement therapy markets in Japan and Western Europe are expected to witness fast and steady growth, partly due to the increasing governmental support and growing demand for enzyme replacement therapy for the treatment of rare diseases.

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Global Enzyme Replacement Therapy Industry: Competitive Landscape

  • Sanofi S.A. (Genzyme Corporation)
  • Shire plc.
  • Pfizer Inc.
  • Alexion Pharmaceuticals Inc.
  • BioMarin Pharmaceutical Inc.
  • Ultragenyx Pharmaceutical Inc.
  • Johnson & Johnson Services Inc.
  • Allergan plc.
  • Leadiant Biosciences Inc.

Pompe Disease Treatment Market Is a type of treatment for certain genetic diseases that are caused by a deficiency in a specific enzyme. This therapy involves administering the missing enzyme to the patient, usually through intravenous infusion.

Key Segments of Enzyme Replacement Therapy Industry Survey

Global Enzyme Replacement Therapy Industry by Therapeutic Condition:

  • Enzyme Replacement Therapy for Fabry Disease
  • Enzyme Replacement Therapy for Gaucher Disease
  • Enzyme Replacement Therapy for Mucopolysaccharidosis
    • MPS I
    • MPS II (Hunter Syndrome)
    • MPS IVA (Morquio Syndrome, Type A)
    • MPS VI (Maroteaux-Lamy Syndrome)
    • MPS VII (Sly Syndrome)
  • Enzyme Replacement Therapy for Pompe Disease
  • Enzyme Replacement Therapy for Lysosomal Acid Lipase Deficiency
  • Others

Global Enzyme Replacement Therapy Industry by Route of Administration:

  • Oral Enzyme Replacement Therapy
  • Injectable Enzyme Replacement Therapy

Global Enzyme Replacement Therapy Industry by Distribution Channel:

  • Hospital Pharmacies
  • Specialty Treatment Pharmacies
  • Retail Pharmacies

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Author

Sabyasachi Ghosh (Associate Vice President at Future Market Insights, Inc.) holds over 12 years of experience in the Healthcare, Medical Devices, and Pharmaceutical industries. His curious and analytical nature helped him shape his career as a researcher.

Identifying key challenges clients face and devising robust, hypothesis-based solutions to empower them with strategic decision-making capabilities come naturally to him. His primary expertise lies in areas such as Market Entry and Expansion Strategy, Feasibility Studies, Competitive Intelligence, and Strategic Transformation.

Holding a degree in Microbiology, Sabyasachi has authored numerous publications and has been cited in journals, including The Journal of mHealth, ITN Online, and Spinal Surgery News.

About Future Market Insights (FMI)

Future Market Insights, Inc. (ESOMAR certified, recipient of the Stevie Award, and a member of the Greater New York Chamber of Commerce) offers profound insights into the driving factors that are boosting demand in the market. FMI stands as the leading global provider of market intelligence, advisory services, consulting, and events for the Packaging, Food and Beverage, Consumer Technology, Healthcare, Industrial, and Chemicals markets. With a team of over 5,000 analysts worldwide, FMI provides global, regional, and local expertise on diverse domains and industry trends across more than 110 countries.

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About the Author

Nikhil Kaitwade

Associate Vice President at Future Market Insights, Inc. has over a decade of experience in market research and business consulting. He has successfully delivered 1500+ client assignments, predominantly in Automotive, Chemicals, Industrial Equipment, Oil & Gas, and Service industries.
His core competency circles around developing research methodology, creating a unique analysis framework, statistical data models for pricing analysis, competition mapping, and market feasibility analysis. His expertise also extends wide and beyond analysis, advising clients on identifying growth potential in established and niche market segments, investment/divestment decisions, and market entry decision-making.
Nikhil holds an MBA degree in Marketing and IT and a Graduate in Mechanical Engineering. Nikhil has authored several publications and quoted in journals like EMS Now, EPR Magazine, and EE Times.

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