In 2022, the global Bullous Keratopathy Market size was estimated to be worth US$ 410 million. The market is expected to be worth US$ 427.54 million by 2023. Throughout the evaluation period of 2023 to 2033, a CAGR of 4.3% is expected, with a closing value of US$ 650 million. The rising prevalence of ocular diseases such as keratoconus, Fuchs dystrophy, and infectious keratitis is propelling the industry’s growth. According to the NCBI study, approximately 10-15% of keratoconus individuals will require corneal implant treatment at some point.
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Corneal blindness, which affects 10 million people worldwide, is the third biggest cause of blindness after glaucoma and cataract. Eye surgery is the most prevalent cause of endothelial layer of the cornea damage. Bullous keratopathy can be caused by trauma, glaucoma, or inflammation from eye surgery. Bullous Keratopathy may occur in 1% to 2% of people undergoing cataract surgery, a small amount when compared to the 10 million cataract surgery patients worldwide each year.
Because of benefits such as low cost, biocompatibility, and enhanced safety and effectiveness, collagen-based bio-engineered artificial corneas used in Bullous Keratopathy are in great demand in the market. Manufacturers are stressing product development and launch. Two items are currently in clinical studies and are likely to contribute to the artificial cornea industry and overall market growth over the forecast period. Corneat Vision, for example, stated that clinical trials for their CorNeat KPro (artificial cornea) are set to begin in 2022. This treatment is likely to be commercialised in 2024, hence adding to the growth of the Bullous Keratopathy market.
Corneal transplantation is the most important treatment for Bullous Keratopathy because it restores endothelial cell form and function. Penetrating keratoplasty (PK), Descemet membrane endothelial keratoplasty (DMEK), and Descemet stripping automated endothelial keratoplasty (DSAEK) are among the procedures available. Between 1999 and 2001, members of the Japan Cornea Society conducted a cross-sectional national survey on 963 eyes with Bullous Keratopathy in Japan. The study looked at demographics, surgical type, complications, and postoperative outcomes. During the study period, bullous keratopathy accounted for 24.2% (963 eyes) of total keratoplasties performed (Shimazaki et al., 2007).
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Key Takeaways from the Market Study
- The global Bullous Keratopathy market is anticipated to be worth US$ 650 million by 2033.
- North America is predicted to have the biggest market share over the projection period.
- Bullous Keratopathy accounted for 19.1% of the market in Europe in 2022.
- Amniotic membrane transplantation is a successful treatment for Bullous Keratopathy because it influences the process of corneal healing, improving visual acuity and reducing subjective symptoms.
- By end-user, the hospital segment dominated the market, accounting for US$ 150 million in sales.
“With major breakthroughs in ophthalmology becoming evident, the scope for Bullous Keratopathy is expected to rise significantly. Moreover, healthcare practitioners are gravitating towards more precise surgeries to improve patient outcomes,” remarks an analyst at FMI.
Competitive Landscape
Key players in the Bullous Keratopathy market are- Hoffmann-La Roche Ltd, Regeneron, Pharmaceuticals, Inc., Pfizer, Inc., Bayer AG, Cellusion, CRSTEurope, Barraquer Eye Hospital, Planchard Eye & Laser Center, Medscape. Some recent developments in Bullous Keratopathy market are:
- In September 2022: Celregen and Cellusion Inc. signed an exclusive license agreement for corneal endothelial cell regenerative therapy in Greater China.
- In July 2022: Carl Zeiss Meditec and Precise Bio announced a partnership in the development and commercialization of tissue-based implants for ophthalmology
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Key Segments Profiled in the Bullous Keratopathy Market Industry Survey
Bullous Keratopathy Market by Therapies:
- Emmecell
- Drug Description
- Regulatory Milestones
- Safety and Efficiency
- Product Profile
- Cellusion
- Drug Description
- Other Development Activities
- Clinical Development
- Safety and Efficiency
- Product Profile
Bullous Keratopathy Market by End User:
- Hospitals
- Surgical Centers
Bullous Keratopathy Market by Treatment:
- Medical Management
- Lubricants
- Steroids
- Hyperosmotic agents
- Anti- Glaucoma drugs
- Antibiotics
- Amniotic Membrane Grafting (AMG)
- Annular Keratotomy
- Anterior Stromal Puncture
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