Tissue Engineered Skin Substitute Market is expected to reach US$ 4.13 Billion by 2029, with CAGR of 9.6%

The global Tissue Engineered Skin Substitute Market size was valued at roughly US$ 2.2 billion in 2022 and is expected to reach US$ 4.13 billion by 2029, according to Future Market Insights (FMI).

The primary factors expected to drive the growth of the tissue engineered skin substitute market are increasing demand for minimally invasive surgeries, a growing geriatric population, an increase in diabetic foot ulcers, an increase in vascular diseases and burn injuries, advancements in healthcare infrastructure, and increased government investment.

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More biomimetic tissue constructs have arisen as a result of tissue engineering and enhanced ability to mix modern manufacturing technologies with biomaterials and cell culture systems. Technological developments are paving the way for the development of advanced tissue engineered skin substitutes. Biotextiles and 3D bioprinting are developing as attractive biofabrication technologies for creating bioengineered skin substitutes. A group of researchers in the United States have found a technology for complete 3D printing of living skin and blood vessels. The emergence of such ground-breaking fabrication technologies will open up a significant opportunity in the worldwide market.

Despite breakthrough innovations assisting the growth of market, certain limitations are still there. The inability of tissue engineered skin substitutes to produce skin appendages such as hair follicles, sebaceous glands, and nails continues to remain among the most concerning challenges facing R&D teams.

Key Takeaways – Tissue Engineered Skin Substitute Market Study

  • The demand for biologic skin substitutes is predicted to rise during the forecast period due to increased research in tissue engineering. A team of engineers from the California Institute of Technology (Caltech) and ETH Zurich, for example, created an artificial skin out of pectin, a naturally occurring long-chain polymer found in plant cell walls that allows the development of natural and fresh dermis.
  • Diabetes and chronic wounds are becoming more common, increasing the demand for tissue engineered skin substitutes.
  • Demand for tissue engineered skin substitutes is predicted to rise in growing economies such as China and India due to an increase in the prevalence of diabetic foot ulcers, venous leg ulcers, and pressure ulcers.

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Leading Manufacturers Setting the Pace for Product Innovations

The tissue engineered skin substitute market is a consolidated market. The tier 1 companies in the tissue engineered skin substitute market such as Allergan Plc., Mimedex Group Inc., Integra LifeSciences Corp. and Integra LifeSciences Corp. are expected to hold more than half of the total revenue generated by tissue engineered skin substitutes. The key players in the market are reshaping their current product portfolio by focusing on the introduction of new and advanced technologies and innovating new products.

Key Players: 

  • Smith & Nephew plc.
  • Acelity L.P. Inc.
  • Mölnlycke Health Care
  • Integra Life Sciences
  • Allergan plc
  • Regenicin
  • Organogenesis Inc.
  • MiMedx
  • LifeNet Health
  • Kerecis
  • Medline Industries, Inc.

Seeking More Insights?

Tissue engineered skin substitute market, a new study from Future Market Insights, opines on the evolution of tissue engineered substitute market from 2014 to 2021 and presents demand projections from 2022 to 2029 on the basis of; product (acellular skin substitute, biologic skin substitute, cellular skin substitute and synthetic substitute), material (synthetic and natural), application (chronic wound, acute wound and other applications such as breast reconstruction etc.) and end user (hospital, specialty clinics, ambulatory surgical centres and research laboratories) across seven prominent regions.

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Tissue Engineered Skin Substitute Market by Category 

By Product:

  • Acellular Skin Substitutes
    • Acellular skin substitutes based on Amniotic Membrane
    • Other Acellular skin substitutes
  • Biologic Skin Substitute
    • Allograft
    • Xenograft
  • Cellular Skin Substitutes
    • Cellular skin substitute based on amniotic membrane
    • Other cellular skin substitutes
  • Synthetic Skin Substitutes

By Material:

  • Synthetic
  • Natural

By Application:

  • Chronic Wounds
    • Venous leg Ulcers
    • Diabetic Foot Ulcer
    • Pressure Ulcers
  • Acute Wounds
    • Traumatic Wounds
    • Burn Cases
  • Other Applications

By End User:

  • Hospital
  • Specialty Clinics
  • Ambulatory Surgical Centers
  • Research Laboratory

About Future Market Insights, Inc.

Future Market Insights, Inc. (ESOMAR certified, Stevie Award – recipient market research organization and a member of Greater New York Chamber of Commerce) provides in-depth insights into governing factors elevating the demand in the market. It discloses opportunities that will favor the market growth in various segments on the basis of Source, Application, Sales Channel and End Use over the next 10-years.

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About the Author

Nikhil Kaitwade

Associate Vice President at Future Market Insights, Inc. has over a decade of experience in market research and business consulting. He has successfully delivered 1500+ client assignments, predominantly in Automotive, Chemicals, Industrial Equipment, Oil & Gas, and Service industries.
His core competency circles around developing research methodology, creating a unique analysis framework, statistical data models for pricing analysis, competition mapping, and market feasibility analysis. His expertise also extends wide and beyond analysis, advising clients on identifying growth potential in established and niche market segments, investment/divestment decisions, and market entry decision-making.
Nikhil holds an MBA degree in Marketing and IT and a Graduate in Mechanical Engineering. Nikhil has authored several publications and quoted in journals like EMS Now, EPR Magazine, and EE Times.

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