According to Future Market Insights (FMI), the global whole genome amplification market size is expected to exceed US$ 5.5 billion by the end of 2033 due to the growing need for whole genome amplification in forensics and genetic disorders. The market is projected to reach sales of US$ 2.8 billion by 2023, with a compound annual growth rate (CAGR) of 7.0% between 2023 and 2033.
Researchers have developed a new method for whole genome amplification called “On-chip cell capture and DNA extraction,” which captures chromosomal DNA from single cells after extraction and fixes it in a micropillar array for isothermal amplification. The advent of single cell on-chip WGA is expected to overcome the amplification biases of standard single cell WGA and improve genome coverage, particularly in cancer cell genomes.
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The convenience of use given by various WGA kits for the entire process has driven the market throughout the years. Molecular testing firms are increasingly focused on developing new devices and kits, such as WGA kits and complete WGA kits with improved capabilities, to increase their revenue share. Adoption of this process is predicted to rise rapidly among research institutes, hospitals, diagnostic centers, and forensic labs, primarily because it provides a more advanced method of genome amplification and sequencing.
Single Cell WGA Continues to Bring in New Applications
The introduction of massively parallel single-cell genome sequencing is expected to expand our understanding of genetic diversity in complex biological systems.
Single cell WGA is a technique for examining sequence information from a single cell using improved next generation sequencing technology. This approach is regarded as a powerful tool for understanding genetics by bringing the full genome structure to a cellular level.
Because this method provides a high-resolution image of the genomic material, its use will grow in a variety of biological domains, including microbiology, immunology, neuroscience, cancer research, and tissue mosaicism.
The key players of the market, including GE Healthcare, Sygnis AG, Illumina, Inc., Merck KGaA, Thermo Fisher Scientific Inc., and Active Motif are inclined more towards strategic acquisitions and mergers.
They are also looking for distribution and collaboration agreements to help improve their product reach. It will also help them serve end users better, with diagnostic consulting and good laboratory practices. High price point may remain a major challenge for companies.
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Key Segments Covered in Whole genome amplification Market Study
By Product Type
- Single Cell WGA Kit
- Complete WGA Kit
- WGA Re-Amplification Kit
- WGA & Chip DNA Kit
- Others
By Application
- Drug Discovery & Development
- Disease Diagnosis
- Agriculture & Veterinary
- Research
- Forensics
- Others
By End User
- Pharma & Biotech Companies
- Hospitals & Clinics
- Contract Research
- Organizations
- Research & Academic Institutes
- Others
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